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1,2 Although the clinical diagnosis of PD relies on the appearance of motor manifestations, extensive neuropathological dissemination initiates decades earlier, posing a significant challenge for early diagnosis

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NAD+ must be administered with a separate syringe and at a different site because its acidic solution can degrade the KLOW peptides on contact

The combination exists only in theoretical pharmacological analysis and, likely, in unsupervised self-experimentation that produces no publishable data

Hanzlikova et al, 2018)